Researchers Crack One of Aromatic Chemistry’s Toughest Challenges

The method has applications in organic chemistry, particularly within the pharmaceutical industry. A team of scientists has developed an electrochemical technique that enables precise, para-position single-carbon insertion into polysubstituted pyrroles. This advancement holds significant promise for synthetic organic chemistry, particularly in the development of pharmaceutical compounds. Their work was recently published in the Journal of [...]

Jul 23, 2025 - 06:00
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Researchers Crack One of Aromatic Chemistry’s Toughest Challenges
Electrochemical Single Carbon Insertion via Distonic Radical Cation IntermediatesThe method has applications in organic chemistry, particularly within the pharmaceutical industry. A team of scientists has developed an electrochemical technique that enables precise, para-position single-carbon insertion into polysubstituted pyrroles. This advancement holds significant promise for synthetic organic chemistry, particularly in the development of pharmaceutical compounds. Their work was recently published in the Journal of [...]

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